Digital Twin Generators

Disease-specific models for generating patients’ digital twins

Our Digital Twin Generators (DTGs) are trained with extensive patient-level historical data to forecast how an individual’s health will change over time.

In addition to our validated DTGs, Unlearn empowers sponsors to securely build and deploy custom DTGs using their proprietary data—within their own environments and under their control.

The Unlearn Platform supports secure, scalable deployment, available either as a web-based application or as a fully secure, on-premises solution within the sponsor’s cloud infrastructure, and meets regulatory-grade compliance standards, including GxP, 21 CFR Part 11, and SOC 2 Type 2. 

With Unlearn’s technology, sponsors maintain complete control over their systems, security, and data integrity—while designing more efficient trials, reducing sample sizes, boosting power, and making faster, more confident development decisions.

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Alzheimer’s Disease (AD)

Alzheimer’s Disease Digital Twin Generator 4.1 (AD DTG 4.1)

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Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis Digital Twin Generator 4.0 (ALS DTG 4.0)

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Frontotemporal Dementia (FTD)

Frontotemporal Dementia Digital Twin Generator 1.2 (FTD DTG 1.2)

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Huntington's Disease (HD)

Huntington's Disease Digital Twin Generator 1.2 (HD DTG 1.2)

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Parkinson's Disease (PD)

Parkinson's Disease Digital Twin Generator 1.2 (PD DTG 1.2)

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Crohn's Disease (CD)

Crohn's Disease Digital Twin Generator 1.1 (CD DTG 1.1)

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Rheumatoid Arthritis (RA)

Rheumatoid Arthritis Digital Twin Generator 1.0 (RA DTG 1.0)

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Atopic Dermatitis (ATD)

Atopic Dermatitis Digital Twin Generator 1.0 (ATD DTG 1.0)

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Psoriasis (PSO)

Psoriasis Digital Twin Generator 1.0 (PSO DTG 1.0)

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Stroke (STR)

Stroke Digital Twin Generator 1.1 (STR DTG 1.1)

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Type 2 Diabetes (T2D)

Type 2 Diabetes Digital Twin Generator 1.0 (T2D DTG 1.0)

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Dyslipidemia (DLD)

Dyslipidemia Digital Twin Generator 1.0 (DLD DTG 1.0)

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Hypertension (HTN)

Hypertension Digital Twin Generator 1.0 (HTN DTG 1.0)

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Major Depressive Disorder (MDD)

Major Depressive Disorder Digital Twin Generator 1.0 (MDD DTG 1.0)

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Neuroscience

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Alzheimer’s Disease (AD)

Alzheimer’s Disease Digital Twin Generator 4.1 (AD DTG 4.1)

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Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis Digital Twin Generator 4.0 (ALS DTG 4.0)

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Frontotemporal Dementia (FTD)

Frontotemporal Dementia Digital Twin Generator 1.2 (FTD DTG 1.2)

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Huntington's Disease (HD)

Huntington's Disease Digital Twin Generator 1.2 (HD DTG 1.2)

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Parkinson's Disease (PD)

Parkinson's Disease Digital Twin Generator 1.2 (PD DTG 1.2)

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Immunology

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Crohn's Disease (CD)

Crohn's Disease Digital Twin Generator 1.1 (CD DTG 1.1)

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Rheumatoid Arthritis (RA)

Rheumatoid Arthritis Digital Twin Generator 1.0 (RA DTG 1.0)

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Atopic Dermatitis (ATD)

Atopic Dermatitis Digital Twin Generator 1.0 (ATD DTG 1.0)

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Psoriasis (PSO)

Psoriasis Digital Twin Generator 1.0 (PSO DTG 1.0)

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Cardio | Metabolic

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Stroke (STR)

Stroke Digital Twin Generator 1.1 (STR DTG 1.1)

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Type 2 Diabetes (T2D)

Type 2 Diabetes Digital Twin Generator 1.0 (T2D DTG 1.0)

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Dyslipidemia (DLD)

Dyslipidemia Digital Twin Generator 1.0 (DLD DTG 1.0)

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Hypertension (HTN)

Hypertension Digital Twin Generator 1.0 (HTN DTG 1.0)

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Musculoskeletal

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Psychiatric

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Major Depressive Disorder (MDD)

Major Depressive Disorder Digital Twin Generator 1.0 (MDD DTG 1.0)

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